I am using 600 cfm carbs on my (2) 350 SBC's. (1) is a 600 Holley, the other a 600 Edelbrock. I am happy with both.
Unless your 350 is a racing motor that turns rpm's in excess of 6500 a 600 cfm is plenty big. You'de be surprised how many people put too big a carb. on their motors. The smaller carb will give a more crisp throttle response and thus be a better choice in regards to driveability.
Nothing can beat what GM used, the Quadrajet. The tiny primarys give excellent economy if you keep your big foot off the pedal and the huge secondarys give a boot in the butt if that's your desire. A lot of people bad mouth them because the first year or so they had their problems but after that they are an excellent carb good for many trouble free miles.
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