With enough cutting and welding, anything is possible. I guess a lot of it comes down to how much money you have, how much time you have, and how much modification are you ok with. One of the immediate concerns would be steering. The V10 will be tight, especially with the exhaust, which may have to be custom fitted for clearances. You will need to use an electric fan, and probably an aftermarket firewall for clearance. Brakes need to be majorly upgraded, bigger the better. That also means bigger wheels. Differential, and driveline need to be fabricated, and front and rear suspension upgraded as well. It will be a lot of work, but so is the vortec upgrade. If done correct, it will be a hell of a ride, if done wrong, it will be a ride from hell. Do a ton of homework before commiting to it. I would probably buy the motor if indeed it is a good deal, as you can always resell it. Get the original engine out of the truck, and do a mock up to see what you will likely deal with for clearances, then have fun........Mike